王荃，研究员，博士生导师。2003年和2008年于南开大学获得生物科学学士学位和微生物学博士学位。作为负责人承担国家及省部级各类科研项目19项。获得天津市“131”创新性人才培养工程第一层次人才，作为主要完成人获得天津市自然科学一等奖。指导学生获得全国大学生基础医学创新论坛暨实验设计大赛三等奖等。 老虎机游戏引进人才，2025年加入老虎机游戏。2008年至2014年于南开大学分别担任讲师和副研究员，2014年进入天津医科大学担任教授。

长期围绕人体微生物和宿主免疫系统的相互作用开展菌源活性物质挖掘和药理学研究：系统揭示炎症性肠病发展中的细菌-免疫互作新机制、抗炎菌源新物质和新靶点；系统研究尿路炎症中的细菌-免疫互作新机制并建立靶向干预新策略。承担19项国家和省部级科研项目（含国家科技重大专项子课题、863项目子课题、国家自然科学基金等），在PNAS、Nature Communications等杂志发表论文60余篇，H指数27。授权专利多项，转让1项。培养博士、硕士20余名。

老虎机游戏

1. Q. Tang#, G. Fan#, X. Peng, X. Sun, X. Kong, L. Zhang, C. Zhang, Y. Liu, J. Yang, K. Yu, C. Miao, Z. Yao, L. Li*, Z. Zhang*, Q. Wang*, Gut bacterial L-lysine induces metabolic and histone methylation to drive dendritic cell tolerance. Cell Rep, 2025, 44:115125. (IF: 6.9)

2. J. Yang#, Y. Xiao#, N. Zhao, G. Pei, Y. Sun, X. Sun, K. Yu, C. Miao, R. Liu, J. Lv, H. Chu, L. Zhou, B. Wang, Z. Yao*, Q. Wang*, PIM1-HDAC2 axis modulates intestinal homeostasis through epigenetic modification. Acta Pharm Sin B, 2024, 14:3049-3067. (IF: 14.8)

3. C. Miao#, Y. Zhang#, G. Liu, J. Yang, K. Yu, J. Lv, R. Liu, Z. Yao, Y. Niu*, X. Wang*, Q. Wang*, Multi-step strategies for synergistic treatment of urinary tract infections based on D-xylose-decorated antimicrobial peptide carbon dots. Biomaterials, 2024. 308: p. 122547. (IF: 12.8)

4. K. Yu#, Q. Li, X. Sun, J. Lv, C. Miao, J. Yang, S. Wang, Z. Fu, Y. Sun, H. Zhang, Z. Zhang, Z. Yao*, Q. Wang*. Bacterial indole-3-lactic acid affects epithelium-macrophage crosstalk to regulate intestinal homeostasis. Proc Natl Acad Sci U S A, 2023,120(45):e2309032120. (IF: 11.1)

5. C. Miao#, Y. Zhang, M. Yu, Y. Wei, C. Dong, G. Pei, Y. Xiao, J. Yang, Z. Yao, Q. Wang*. HSPA8 regulates anti-bacterial autophagy through liquid-liquid phase separation. Autophagy, 2023,19(10):2702-2718. (IF: 13.3)

6. J. Yang#, G. Pei#, X. Sun, Y. Xiao, C. Miao, L. Zhou, B. Wang, L. Yang, M. Yu, Z. Zhang, E.  Keller, Z. Yao, Q. Wang*. RhoB Affects Colitis through Modulating Cell Signaling and Intestinal Microbiome. Microbiome, 2022, 10:149. (IF: 16.8)

7. Q. Li#, X. Sun#, K. Yu#, J. Lv, C. Miao, J. Yang, S. Wang, Z. Fu, Y. Sun, H. Zhang, Z. Zhang, E. Keller, Z. Yao*, Q. Wang*. Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance. Cell Rep, 2022, 40:111308. (IF: 10.0)

8. X. Sun#, J. Yang#, X. Deng#, Y. Wei, C. Wang, Y. Guo, H. Yang, L. Yang, C. Miao, J. Lv, Y. Xiao, H. Zhang, Z. Yao*, and Q. Wang*, Interactions of Bacterial Toxin CNF1 and Host JAK1/2 Driven by Liquid-Liquid Phase Separation Enhance Macrophage Polarization. mBio, 2022, 13(4): e0114722. (IF: 7.8)

9. C. Miao#, M. Yu#, G. Pei, Z. Ma, L. Zhang, J. Yang, J. Lv, Z. Zhang, E. Keller, Z. Yao*, Q. Wang*. An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli. Nat Commun, 2021, 12:2587. (IF: 14.9)

10. X. Li#, G. Pei#, L. Zhang, Y. Cao, J. Wang, L. Yu, W. Dianjun, S. Gao, Z. S. Zhang, Z. Yao, Q. Wang*, Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder. EBioMedicine, 2019, 50: 23-33. (IF: 6.7)