王朝辉，研究员，博士生导师。2006年毕业于郑州大学，获得药物制剂学士学位。2009年毕业于沈阳药科大学，获得药剂学硕士学位。2012年毕业于北京大学，获得药剂学博士学位。获得国家级优秀青年人才项目资助，以及辽宁省自然科学奖论文类一等奖等荣誉。
     老虎机游戏引进人才，2020年加入老虎机游戏，曾在美国普渡大学、德克萨斯大学西南医学中心从事科学研究工作。

长期从事智能药物递送系统及其在肿瘤免疫治疗中的应用研究。立足于实体瘤疗效不佳的难题，系统性探索了递送载体的理性设计，提出和发展了不同作用机制协同增效的抗肿瘤免疫治疗策略。迄今发表学术论文40余篇，包括以第一和通讯作者在Nature Nanotechnology、Advanced Materals、Angewandte Chemie International Edition、Nano Letters、ACS Nano等期刊发表论文多篇，承担多项国家和省部级科研项目，参与英文专著及十四五规划教材各1章节，授权美国及澳大利亚专利各1项，研究成果技术转移2项。

老虎机游戏

1. Zhou M#, Liang S#, Wang J#, Hai L#, Peng Y, Xiong Q, Liu D, Ma K, Yun K, Wang Z*. A Rationally Designed Cyclic Dinucleotide Amplifier Potentiating STING Activation for Cancer Immunotherapy. Advanced Functional Materials 2025, 35(24): 2414918. (IF=18.5)

2. Liang S#, Ma H#, Liu Y, Hai L, Tian Y, Sun Y, Wang Z*. Nano-immunomodulator amplifies STING activation in tumor-associated macrophages for cancer immunotherapy. Journal of Controlled Release 2025, 383: 113846. (IF=11.5)

3. Liu D#, Liang S, Ma K, Meng Q, Li X, Wei J, Zhou M, Yun K, Pan Y, Rao L*, Chen X*, Wang Z*. Tumor Microenvironment-Responsive Nanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy. Advanced Materials 2024, 36(5): e2304845. (IF=27.4)

4. Peng Y#, Liang S, Liu D, Ma K, Yun K, Zhou M, Hai L, Xu M, Chen Y, Wang Z*. Multi‐Metallic Nanosheets Reshaping Immunosuppressive Tumor Microenvironment through Augmenting cGAS‐STING Innate Activation and Adaptive Immune Responses for Cancer Immunotherapy. Advanced Science 2024, 11(38): 2403347. (IF=15.1)

5. Liang S#, Ma M#, Li X#, Yun K, Meng Q, Ma K, Liu D, Yue L, Rao L*, Chen X*, Wang Z*. A Guanidinobenzol-Rich Polymer Overcoming Cascade Delivery Barriers for CRISPR-Cas9 Genome Editing. Nano Letters 2024, 24(23): 6872-6880. (IF=10.8，封面)

6. Pan Y#, Liu L, Zhang J, Liang S, Parshad B, Lai J, Ma L*, Wang Z*, Rao L*. Genetically Engineered Nanomodulators Elicit Potent Immunity against Cancer Stem Cells by Checkpoint Blockade and Hypoxia Relief. Bioactive Materials 2024, 38: 31-44. (IF=18.9)

7. D Liu#, S Liang#, K Ma, K Yun, M Zhou, J Yao, L Hai, Y Peng, Z Wang*. A bi-adjuvant nanovaccine amplifying STING activation for cancer immunotherapy. Nano Today 2024, 57: 102372. (IF=13.1)

8. Liang S#, Yao J, Liu D, Rao L^*, Chen X^*, Wang Z^*. Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy. Advanced Materials 2023, 35(33): e2211130. (IF=27.4)

9. Luo M^#, Wang H^#, Wang Z^#, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka M, Lea J, Frankel A, Fu Y, Chen Z*, Gao J*. A STING-activating nanovaccine for cancer immunotherapy. Nature Nanotechnology 2017, 12: 648-654. (IF=39.2，ESI高被引)

10. Wang Z#, Luo M#, Mao C, Wei Q, Zhao T, Li Y, Huang G, Gao J*. A redox-activatable fluorescent sensor for the high-throughput quantification of cytosolic delivery of macromolecules. Angewandte Chemie International Edition 2017, 129: 1339-1343. (IF=16.9)