王洪，研究员，博士研究生导师。获国家高层次青年拔尖人才，国家高层次留学回国人才，天津市“杰青”、科技创新领军人才等称号。主持国家自然科学基金专项和面上等项目。研究成果获2023年度中国血液学十大研究进展；人类蛋白质组学组织HUPO（领域最权威国际学会）2023年度亮点成果奖‘Proteomics Highlight of Year’（亚洲唯一入围并获奖）。 老虎机游戏引进人才，2021年加入老虎机游戏。曾在美国圣裘德儿童研究医院结构生物系从事博士后研究，随后在该院蛋白质组学中心任研究员。

长期从事前沿组学技术开发和多组学驱动的血液精准医学研究。以通讯/第一作者在Immunity、Cancer Cell、Nature Communications、PNAS、Molecular Neurodegeneration、Genome Biology等发表研究论文多篇；申请专利以及软著6项，授权4项；实现成果转化1项（50万）；启动研究者发起的IIT临床试验2项，成果相关新药获批IND并已进入III期临床试验。担任亚太人类蛋白质组协会（AOHUPO）委员、中国生物化学与分子生物学会蛋白质组学分会委员、中国生理学会整合生理学专委会委员、天津市分析测试协会常务理事。

老虎机游戏

1. Dandan Yang#, Tingting Zhang#, Yang Yang#, Dong Zhang, Zhiwei Zhou, Ning Wang, Jinting Fan, Chenghua Xu, Youyang Fang, Lichun Kang, Mingming Niu, Chunliang Li, Long Shen?, Hong Wang?. Integration of CRISPR-Cas9 screens and multi-omics profiling reveals chromodomain helicase DNA binding protein 7-angiopoietin-1 as a novel multidrug resistance axis in acute myeloid leukemia. Interdisciplinary Medicine. 2025. e70053. (IF:13.6)

2. Wenchang Qian#, Penglei Jiang#, Mingming Niu#, Yujuan Fu#, Deyu Huang, Dong Zhang, Ying Liang, Qiwei Wang, Yingli Han, Xin Zeng, Yixin Shi, Lingli Jiang, Zebin Yu, Jinxin Li, Huan Lu, Hong Wang*, Baohui Chen?, Pengxu Qian?. Selective identification of epigenetic regulators at methylated genomic sites by SelectID. Nature Communications. 2025.16(1): 3709. (IF: 15.7)

3. Mingming Niu#, Ning Wang#, Dandan Yang#, Lixia Fu#, Yang Yang, Long Shen, Hong Wang*, Xianfeng Shao?. Multi-omics integration reveals immune hallmarks and biomarkers associated with FLT3 inhibitor sensitivity in FLT3-mutated AML. Blood Science. 7(2):p e00227, June 2025. (IF: 2.7)

4. Hong Wang#?, Tao Cheng?. Towards a blood ecosystem approach to dissect systemic diseases. Sci China Life Sci. 2024. 67 (7), 1528-1531. (IF:9.5)

5. Hong Wang#?, Cuicui Liu#, Xiaowei Xie#, Mingming Niu#, Yingrui Wang#, Xuelian Cheng#, Biao Zhang#, Dong Zhang, Mengyao Liu, Rui Sun, Yezi Ma, Shihui Ma, Huijun Wang, Guoqing Zhu, Yang Lu, Baiming Huang, Pei Su, Xiaoyuan Chen, Jingjing Zhao, Hongtao Wang, Long Shen, Lixia Fu, Qianqian Huang, Yang Yang, He Wang, Chunlong Wu, Weigang Ge, Chen Chen, Qianyu Huo, Qingping Wang, Ying Wang, Li Geng, Yan Xie, Yi Xie, Lijun Liu, Jianwei Qi, Huaiyong Chen, Junping Wu, Erlie Jiang, Wentiao Jiang, Ximo Wang?, Zhongyang Shen?, Tiannan Guo?, Jiaxi Zhou?, Ping Zhu?, Tao Cheng?. Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection. Immunity. 2023.56(6):1410-1428. (IF: 25.5)

6. Shaela Wright#, Jianzhong Hu#, Hong Wang#, Judith Hyle, Yang Zhang, Guoqing Du, Marina Y Konopleva, Steven M Kornblau, Mohamed Nadhir Djekidel, Wojciech Rosikiewicz, Beisi Xu, Rui Lu, Jun J Yang*, Chunliang Li*. Interrogating bromodomain inhibitor resistance in KMT2A-rearranged leukemia through combinatorial CRISPR screens. Proc Natl Acad Sci USA. 2023. Apr 18;120(16):e2220134120. (IF: 9.4)

7. Hong Wang#*, Kaushik Kumar Dey#, Ping-Chung Chen, Yuxin Li, Mingming Niu, Ji-Hoon Cho, Xusheng Wang, Bing Bai, Yun Jiao, Surendhar Reddy Chepyala, Vahram Haroutunian, Bin Zhang, Thomas G. Beach and Junmin Peng*. Integrated analysis of ultra-deep proteomes in cortex, cerebrospinal fluid and serum reveals a mitochondrial signature in Alzheimer’s disease. Molecular Neurodegeneration. 2020.15(1):43. (IF: 14.195, C100)

8. Hong Wang#, Alexander K Diaz, Timothy I Shaw, Yuxin Li, Mingming Niu, Ji-Hoon Cho, Barbara S Paugh, Yang Zhang, Jeffrey Sifford, Bing Bai, Zhiping Wu, Haiyan Tan, Suiping Zhou, Laura D Hover, Heather S Tillman, Abbas Shirinifard, Suresh Thiagarajan, Andras Sablauer, Vishwajeeth Pagala, Anthony A High, Xusheng Wang, Chunliang Li, Suzanne J Baker*, Junmin Peng*. Deep multi-omics profiling of brain tumors identifies signaling networks downstream of cancer driver genes. Nature Communications. 2019.10(1):3718. (IF: 12.121)

9. Elizabeth Stewart#, Justina McEvoy#, Hong Wang#, Xiang Chen#, Victoria Honnell, Monica Ocarz, Brittney Gordon, Jason Dapper, Kaley Blankenship, Yanling Yang, Yuxin Li, Timothy I Shaw, Ji-Hoon Cho, Xusheng Wang, Beisi Xu, Pankaj Gupta, Yiping Fan, Yu Liu, Michael Rusch, Lyra Griffiths, Jongrye Jeon, Burgess B Freeman III, Michael R Clay, Alberto Pappo, John Easton, Sheila Shurtleff, Anang Shelat, Xin Zhou, Kristy Boggs, Heather Mulder, Donald Yergeau, Armita Bahrami, Elaine R Mardis, Richard K Wilson, Jinghui Zhang, Junmin Peng, James R Downing, Michael A Dyer*, St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project. Identification of Therapeutic Targets in Rhabdomyosarcoma Through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. 2018.34(3):411-426.e19. (IF:23.9)

10. Hong Wang#, Yanling Yang, Yuxin Li, Bing Bai, Xusheng Wang, Haiyan Tan, Tao Liu, Thomas G Beach, Junmin Peng?, Zhiping Wu?. Systematic optimization of long gradient chromatography mass spectrometry for deep analysis of brain proteome. Journal of Proteome Research. 2015 14(2):829-38. (IF: 4.173, C100)