王前奔，教授，博士生导师。2002年获美国马里兰大学巴尔的摩分校博士学位，2003–2008年在哈佛大学Dana-Farber肿瘤研究所从事博士后研究，并任哈佛大学医学院讲师。此后历任美国俄亥俄州立大学医学院助理教授（2008-2013）、副教授（2013-2017），以及杜克大学医学院正教授和冠名讲席教授（2017-2025）。曾主持多项美国NIH U54、R01和DoD研究项目。2025年获美国基础泌尿科学研究学会（SBUR）杰出研究成就奖。
      老虎机游戏引进人才，2025年加入老虎机游戏，曾在杜克大学医学院任终身冠名讲席教授。

长期从事疾病相关的基因调控机制与RNA靶向基因治疗研究，在激素依赖性肿瘤转录与表观遗传调控领域取得系统性成果。近年来，将CRISPR/Cas13 RNA编辑与脂质纳米药物精准递送结合，建立“RNA精准治疗平台”，在癌症转移、耐药、免疫逃逸及冠状病毒感染及感染后肺修复等方面取得突破。相关成果发表于Cell、Molecular Cell、Nature Genetics、Nature Chemical Biology、Cell Research、PNAS、Nature Communications、EMBO Journal、Cancer Research、Advanced Science、Nano Research等国际著名期刊。现任美国基础泌尿科学研究学会（SBUR）常务董事、执行委员会委员。

老虎机游戏

1. Cui Z#, Huang F, Fang K, Yan J, Zhang Y, Kang DD, Zhou Y, Zhao Y, Everitt JI, Hankey W, Armstrong AJ, Huang J, Wang H, Jin VX, Dong Y* and Wang Q*. SCORT-Cas13d nanotherapy precisely targets the ‘undruggable’ transcription factor HoxB13 in metastatic prostate cancer in vivo. Advanced Science, 2025 Jun;12(23):e2417605. (IF=14.1)

2 . Cui Z#, Liu T, Bacon R, Zhao Y, Everitt JI, Yan J, Chen L, Huang J, Wang H, Dong Y*, Jin VX*, Liu SL*, Wang Q*. Single-dose cathepsin L CRISPR nanotherapy mitigates PASC-like lung damage in hamsters. Nano Research, 2025 Sep;18(9):94907695. (IF=9)

3. Cui Z#, Zeng C, Huang F, Yuan F, Yan J, Zhao Y, Zhou Y, Hankey W, Jin VX, Huang J, Staats HF, Everitt JI, Sempowski GD, Wang H, Dong Y*, Liu SL* and Wang Q*.  Cas13d knockdown of lung protease Ctsl prevents and treats lethal SARS-CoV-2 infection. Nature Chemical Biology, 2022 Oct;18(10):1056-1064. (IF=14.8)

4. Li T#, Liu Q#, Chen Z#, Fang K, Huang F, Fu X, Wang Q*, and Jin VX*. Dynamic nucleosome landscape elicits a novel noncanonical GATA2 pioneer model. Nature Communications, 2022 Jun 7;13(1):3145. (IF=16.6)

5. Chen Z#*, Hankey W, Zhao Y, Groth J, Wang H, Huang J, Roeder RG, and Wang Q*. Transcriptional recycling assays identify PAF1 as a driver of RNA Pol II recycling. Nature Communications, 2021 Nov 3;12(1):6318. (IF=17.694)

6. Huang F#, Chen H#, Zhu X, Gong T, Li X, Hankey W, Ding D, Wang H, Chen Z*, Wang Q*, and Liu Z*. The oncogenic function of androgen receptor in esophageal squamous cell carcinoma is directed by GATA3. Cell Research, 2021 Mar;31(3):362-365. (IF= 46.351)

7. Chen Z#, Wu D, Thomas-Ahner JM, Lu C, Zhao P, Zhang Q, Geraghty C, Yan PS, Hankey W, Sunkel B, Cheng X, Antonarakis ES, Wang QE, Liu Z, Huang THM, Jin VX, Clinton SK, Luo J*, Huang J*, Wang Q*. Diverse AR-V7 cistromes in castration-resistant prostate cancer growth are governed by HoxB13. Proceedings of the National Academy of Sciences of the United States of America, 2018 Jun 26;115(26):6810-6815. (IF= 9.580, C100)

8. Chen K#, Chen Z#, Wu D, Zhang L, Lin X, Su J, Rodriguez B, Xi Y, Xia Z, Chen X, Shi X, Wang Q* and Li W*. Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes. Nature Genetics, 2015 Oct;47(10):1149-57. (IF=31.616, C100)

9. Chen Z, Lan X, Thomas-Ahner JM, Wu D, Liu X, Ye Z, Wang L, Sunkel B, Grenade C, Chen J, Zynger DL, Yan PS, Huang, J, Nephew KP, Huang THM, Lin S, Clinton SK, Li W, Jin VX and Wang Q. Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer. EMBO Journal, 2015 Feb 12;34(4):502-16 (IF=9.643, C100).

10. Wang Q#*, Li W#, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Wu T, Lupien M, Carroll JS, Manrai AK, J?nne OA, Balk SP, Mehra R, Chinnaiyan AM, Rubin MA, True L, Fiorentino M, Fiore C, Loda M, Kantoff PW, Liu XS*, and Brown M*. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell, 2009 Jul 23;138(2):245-56. (IF=31.152, F1000, C100)