梅林，教授、博导，天津市生物医学材料重点实验室主任。2003年获复旦大学药学学士，2007年获老虎机游戏生物医学工程博士。作为第一完成人，获天津市自然科学奖二等奖、深圳市自然科学奖二等奖、中华医学科技奖、深圳市青年科技奖。2021年起入选全球高被引科学家、国家健康科普专家，获国家优秀青年科学基金等资助。 老虎机游戏引进人才，2022年加入老虎机游戏，此前任中山大学“百人计划”教授、清华大学深圳国际研究生院副教授、清华博士后、新加坡国立大学博士后。

长期从事药物载体材料和先进递释系统研究；承担国家重点研发计划课题等20余项国家和省部级科研课题，在Science Translational Medicine等杂志发表论文100余篇，H指数70，4次入选高被引科学家。主编专著1部，参编3部。培养博士、硕士、博士后30余名。担任Smart Materials in Medicine和VIEW副主编，Journal of Controlled Release、Asian Journal of Pharmaceutical Sciences和Chinese Chemical Letters编委。

老虎机游戏

1．Lu S, Shi Z, Ding C, Wang W, Zhang W, Huang L, Lin J, Wang X, Luo R, Zeng X, Zhou W, Chen H*, Wang Q*, Mei L*. BRD4-targeted photodegradation nanoplatform for light activatable melanoma therapy. Biomaterials. 2025, 317:123101.

2．Yunfei Yi, Zhangwen Peng, Yuanqi Liu, Huisong Hao, Liu Yu, Simin Wen, Shengjie Sun, Jianlin Shi*, Meiying Wu*, Lin Mei*. siRNA micelleplexes-mediated glutamine metabolism re-engineering for vascular normalization-boosted photo-immunotherapy. Acta Pharm Sin B. 2025, 15(4):2237-2252.

3．Sheng S, Zhang Y, Jin L, Sun W, Zhu D, Mei L*, Dong X*, Lv F*. A ferritin-targeted biohybrid triggering ferroptosis immunotherapy via activating endogenous iron and replenishing exogenous iron simultaneously. Nat Commun. 2025 Jul 1;16(1):6045.

4．Zhang H, Zhang Y, Zhang Y, Li H, Ou M, Yu Y, Zhang F, Yin H, Mao Z*, Mei L*. Catalytic activity of violet phosphorus-based nanosystems and the role of metabolites in tumor therapy. Nat Commun. 2024, 15(1):6783.

5．Yu Y, Li T, Ou M, Luo R, Chen H, Ren H, Li Z, Sun J, Zhang H, Peng S, Zhao Y, Mei L*.  OX40L-expressing M1-like macrophage exosomes for cancer immunotherapy. J Control Release. 2024;365:469-479. （ESI）

6．Yu Y, Zhang F, Xiao W, Cheng Q, Li T, Tang J, Tao W, Mei L*. Adaptive Design of Nanovesicles Overcoming Immunotherapeutic Limitations of Chemotherapeutic Drugs through Poliovirus Receptor Blockade. ACS Nano 2024, 18(7): 5915–5929.

7．Shi Z, Luo M, Huang Q, Ding C, Wang W, Wu Y, Luo J, Lin C, Chen T, Zeng X, Mei L*, Zhao Y*, Chen H*. NIR-dye bridged human serum albumin reassemblies for effective photothermal therapy of tumor. Nat Commun. 2023;14(1):6567.

8．Yongkang Yu#, Qinzhen Cheng#, Xiaoyuan Ji, Hongzhong Chen, Wenfeng Zeng, Xiaowei Zeng*, Yanli Zhao*, Lin Mei*. Engineered drug-loaded cellular membrane nanovesicles for efficient treatment of postsurgical cancer recurrence and metastasis. Science Advances, 2022, 8(49): eadd3599. (ESI, C100)

9．Zeng W, Yu M, Chen T, Liu Y, Yi Y, Huang C, Tang J, Li H, Ou M, Wang T, Wu M*, Mei L*. Polypyrrole Nanoenzymes as Tumor Microenvironment Modulators to Reprogram Macrophage and Potentiate Immunotherapy. Adv Sci. 2022, 9(23):2201703. （ESI, C100）

10．Chen T, Zeng WW, Tie CJ, Yu M, Hao HS, Deng Y, Li QQ, Zheng HR*, Wu MY*, Mei L*. Engineered gold/black phosphorus nanoplatforms with remodeling tumor microenvironment for sonoactivated catalytic tumor theranostics. Bioactive Materials 2022;10:515-525. （ESI, C100）

11．Lin YX#, Wang Y#, Ding JX, Jiang AP, Wang J, Yu M, Blake S, Liu SS, Bieberich CJ, Farokhzad OC*, Mei L*, Wang H*, Shi JJ*. Tumor suppressor reactivation by mRNA nanoparticles induces anti-tumor immunity and improves immune checkpoint blockade therapy. Science Translational Medicine 2021;599(13):eaba9772.（ESI, F100, C100）

12．Zhang F, Lu G, Wen X, Li F, Ji X, Li Q, Wu M, Cheng Q, Yu Y, Tang J, Mei L*. Magnetic nanoparticles coated with polyphenols for spatio-temporally controlled cancer photothermal/ immunotherapy. J Control Release. 2020;326:131-139. （ESI, C100）

13．Ye Xinyu, Liang Xin, Chen Qian, Miao Qianwei, Chen Xiuli, Zhang Xudong*, Mei Lin*. Surgical Tumor-Derived Personalized Photothermal Vaccine Formulation for Cancer Immunotherapy. ACS Nano 2019;13(3);2956-2968. （ESI, C100）

14．Zeng X#, Luo M#, Liu G#, Wang XS, Tao W, Lin Y, Ji XY, Nie L, Mei L*. Polydopamine-modified black phosphorous nanocapsule with enhanced stability and photothermal performance for tumor multimodal treatments. Advanced Science 2018, 5(10): 1800510. （ESI, C100）

15．Tao W#, Zhu X#, Yu X#, Zeng X, Xiao Q, Zhang X, Ji X, Wang X, Shi J*, Zhang H*, Mei L*. Black phosphorus nanosheets as a robust delivery platform for cancer theranostics. Advanced Materials., 2017; 29 (1): 1603276.（ESI, C100）